pentobarbital will lessen the extent or result of darifenacin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
pentobarbital will minimize the extent or effect of bortezomib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
pentobarbital improves toxicity of buprenorphine, prolonged-performing injection by pharmacodynamic synergism. Modify Therapy/Keep an eye on Closely. Coadministration of buprenorphine and benzodiazepines or other CNS depressants will increase risk of adverse reactions like overdose, respiratory despair, and Demise. Cessation of benzodiazepines or other CNS depressants is most well-liked typically.
pentobarbital will minimize the extent or result of triazolam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
pentobarbital will minimize the level or effect of disopyramide by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unfamiliar.
pentobarbital will minimize the level or result of abiraterone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
pentobarbital will decrease the extent or outcome of atorvastatin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will reduce the extent or outcome of theophylline by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
pentobarbital will lower the level or impact of celecoxib by affecting hepatic enzyme CYP2C9/ten metabolism. Insignificant/Importance Unfamiliar.
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pentobarbital will minimize the level or outcome of ziprasidone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Mysterious.
Keep track of Intently (1)pentobarbital will minimize the level or effect of fentanyl by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Carefully. Coadministration of fentanyl with CYP3A4 inducers could lead into a decrease in fentanyl plasma concentrations, insufficient efficacy or, possibly, improvement of the withdrawal syndrome inside a affected individual who has designed physical dependence to fentanyl. After halting a CYP3A4 inducer, since the effects from the inducer decrease, the fentanyl plasma focus will raise which could improve or extend both the therapeutic and adverse effects.
C: Use with caution if Rewards outweigh challenges. Animal experiments display threat and human reports not out there or neither animal nor human studies carried out.